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L-lysine degradation I

State Icon Reaction EC-Number Confidence maximal confidence score from EnzymeDetector
(S)-2-hydroxyglutarate + electron-transfer_quinone <=> 2-oxoglutarate + electron-transfer_quinol 1.1.5.13 (S)-2-hydroxyglutarate dehydrogenase

5-Oxopentanoate + NADP+ + H2O <=> Glutarate + NADPH + H+ 1.2.1
1.2.1.20 glutarate-semialdehyde dehydrogenase


Glutarate + 2-oxoglutarate + O2 <=> (S)-2-hydroxyglutarate + succinate + CO2 1.14.11.64 glutarate dioxygenase

L-lysine + H+ <=> cadaverine + CO2 4.1.1.17 ornithine decarboxylase
4.1.1.18 lysine decarboxylase
4.1.1.19 arginine decarboxylase
4.1.1.50 adenosylmethionine decarboxylase
4.1.1.86 diaminobutyrate decarboxylase
4.1.1.B12






cadaverine + 2-oxoglutarate <=> 5-Aminopentanal + L-glutamate 2.6.1
2.6.1.19 4-aminobutyrate---2-oxoglutarate transaminase
2.6.1.29 diamine transaminase
2.6.1.82 putrescine---2-oxoglutarate transaminase




5-Aminopentanoate + 2-oxoglutarate <=> L-glutamate + 5-Oxopentanoate 2.6.1.19 4-aminobutyrate---2-oxoglutarate transaminase
2.6.1.2 alanine transaminase
2.6.1.48 5-aminovalerate transaminase



5-Aminopentanal + NAD+ + H2O <=> 5-Aminopentanoate + NADH + H+ 1.2.1.19 aminobutyraldehyde dehydrogenase
1.2.1.3 aldehyde dehydrogenase (NAD+)


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